This guidance note, developed by CDC Group in partnership with the 2X Challenge and the Global Impact Investing Network (GIIN), provides a practical framework for investors to measure and report the gender impact of their investments. By aligning the 2X Challenge criteria with the IRIS+ system of standardized impact metrics, it enables consistency across portfolios and comparability across institutions. The document sets out how to apply gender indicators in five key areas—entrepreneurship, leadership, employment, consumption, and investments through intermediaries—while also providing guidance on data collection, reporting, and alignment with broader impact measurement standards.